Head-to-Head vs. Adalimumab

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Efficacy outcomes at Week 12 - Exploratory analysis of the FINCH 1 trial2,8

Consistent head-to-head results vs. adalimumab in MTX-IR patients2,8

Adapted from Combe B, et al. 20212 and Data on file, Gilead Sciences Ltd8
Exploratory analysis of the FINCH 1 trial. All trial patients were included. *Pre-specified, non-ranked endpoints/analysis. †Post-hoc analysis.

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ACR Data


Radiographic Progression

DAS28-CRP Remission

JYSELECA is indicated for the treatment of moderate to severe active rheumatoid arthritis in adult patients who have responded inadequately to, or who are intolerant to one or more disease modifying anti-rheumatic drugs (DMARDs).1 JYSELECA may be used as monotherapy or in combination with methotrexate (MTX).1

References: 1. JYSELECA SPC. Available at: www.medicines.org.uk / www.medicines.ie. Last accessed: October 2022. 2. Combe B, et al. Ann Rheum Dis 2021;doi:10.1136/annrheumdis-2020-219214. 3. Genovese MC, et al. JAMA 2019;322 (4):315–325. 4. Westhovens R, et al. Ann Rheum Dis 2021;doi:10.1136/annrheumdis-2020-219213. 5. Combe B, et al. Arthritis Rheumatol 2021;73(suppl 10). https://acrabstracts.org/abstract/clinical-outcomes-up-to-week-48-of-filgotinib-treatment-in-an-ongoing-long-term-extension-trial-of-ra-patients-with-inadequate-response-to-mtx-initially-treated-with-filgotinib-or-adalimumab-during-th/. Last accessed: October 2022. 6. Buch MH, et al. Arthritis Rheumatol 2021;73 (suppl 10). https://acrabstracts.org/abstract/clinical-outcomes-up-to-week-48-of-ongoing-filgotinib-ra-long-term-extension-trial-of-biologic-dmard-inadequate-responders-initially-on-filgotinib-or-placebo-in-a-phase-3-trial/. Last accessed: October 2022. 7. Data on file - Gilead Sciences Ltd - INF-UK-20-04. 8. Data on file - Gilead Sciences Ltd - INF-UK-20-06. 9. Data on file - Gilead Sciences Ltd - INF-UK-20-11.

UK-RA-JY-202203-00018  | Date of preparation December 2022